| ncRNA name | hsa-miR-21-5p |
| ncRNA Category | miRNA |
| Disease name | Graves disease |
| Species | Homo sapiens |
| Tissues/Cell_line | thyroid tissues, blood |
| Methods | next-generation sequencing, qRT-PCR |
| Expression pattern | up-regulated |
| Functional description | miRNA-21-5p was associated with a higher risk of developing GD and a worse clinical outcome, and it was correlated to persistent disease in the long-term follow-up, with a better predictive value than the currently used TRAb levels.miR-21-5p can regulate the Th1/Th2 balance and promote Th17 differentiation by inhibiting Smad-7. |
| PubMed ID | 29325052 |
| Year | 2018 |
| Title | A MicroRNA Signature for Evaluation of Risk and Severity of Autoimmune Thyroid Diseases. |
| Drug-related ncRNA | NO |
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